Second Issue: Apr 30, 2015; Vol. 1; No. 2

On The Cover: Strategies to target tumor-associated macrophages (TAMs) for therapeutic purposes. TAMs can be targeted using two different approaches: through the direct depletion of macrophages and the inhibition of monocyte recruitment (Reduce), or by restoring their anti-tumoral cytotoxic function (Re-activate). See details at: Cancer Research Frontiers. 2015 Apr; 1(2): 149-161. doi: 10.17980/2015.149

Reviews

Iterative data multiplexing (IDM) supports elucidation of drug targets from functional genomics screening approaches.
Emma Shanks.
Cancer Research Frontiers. 2015 Apr; 1(2): 119-126. doi: 10.17980/2015.119
Abstract _ Full Text (HTML) _ Full Text (PDF)

 

Managing Advanced Melanoma: Targeting the PD-1 Pathway with Pembrolizumab.
Sylvana Ho, In S. Kang, Marcus C Ravnan.
Cancer Research Frontiers. 2015 Apr; 1(2): 127-137. doi: 10.17980/2015.127
Abstract _ Full Text (HTML) _ Full Text (PDF)

 

New Insights into Laryngeal Squamous Cell Carcinoma: Cancer Stem-Like Cells.
Esra Guzel, Omer Faruk Karatas, Mete Emir Ozgurses, Mustafa Ozen.
Cancer Research Frontiers. 2015 Apr; 1(2): 138-148. doi: 10.17980/2015.138
Abstract _ Full Text (HTML) _ Full Text (PDF)

 

Tumor-associated macrophages, multi-tasking cells in the cancer landscape.
Giulia Marelli, Paola Allavena, Marco Erreni
Cancer Research Frontiers. 2015 Apr; 1(2): 149-161. doi: 10.17980/2015.149
Abstract _ Full Text (HTML) _ Full Text (PDF)

 

Localized Management of Soft Tissue Sarcoma Metastasis: A Review of a Multidisciplinary Approach.
Meena Bedi, David M. King, Hina Saeed, Sean Tutton, John A. Charlson, Donald A. Hackbarth, John C. Neilson.
Cancer Research Frontiers. 2015 Apr; 1(2): 162-171. doi: 10.17980/2015.162
Abstract _ Full Text (HTML) _ Full Text (PDF)

 

Cell-derived Extracellular Vesicles Open New Perspectives for Cancer Research.
Irène Tatischeff
Cancer Research Frontiers. 2015 Apr; 1(2): 208-224. doi: 10.17980/2015.208
Abstract _ Full Text (HTML) _ Full Text (PDF) 

 

 

 

Research Articles

Detection and differentiation of paediatric renal tumours using diffusion-weighted imaging: an explorative retrospective study.
Isabel Platzer, Mengxia Li, Beate Winkler, Philipp Schweinfurth, Thomas Pabst, Thorsten Bley, Henning Neubauer.
Cancer Research Frontiers. 2015 Apr; 1(2): 178-190. doi: 10.17980/2015.178
Abstract _ Full Text (HTML) _ Full Text (PDF) 

 

CT and MRI Evaluation of Nasal Adenocarcinoma Local Extent.
Patrice GALLET, Philippe HENROT, Bruno GRIGNON, Phi Linh NGUYEN THI, Roger JANKOWSKI.
Cancer Research Frontiers. 2015 Apr; 1(2): 191-199. doi: 10.17980/2015.191
Abstract _ Full Text (HTML) _ Full Text (PDF)

 

An Intravital Multiphoton Microscopy Model for visualization of tumor cell dissemination and lymphatic vasculature.
Katharina Eder, Steffen Dietzel, Ulrich Harreus, Brigitte Mack, Manuel Guhlich, Carola Eggert, Alexander Berghaus, Olivier Gires, Martin Canis.
Cancer Research Frontiers. 2015 Apr; 1(2): 200-207. doi: 10.17980/2015.200
Abstract _ Full Text (HTML) _ Full Text (PDF)