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Research Article

Cancer Research Frontiers. 2015 Apr; 1(2): 191-199. doi: 10.17980/2015.191

CT and MRI Evaluation of Nasal Adenocarcinoma Local Extent

Patrice GALLET1,2[*], Philippe HENROT2,3, Bruno GRIGNON2,3, Phi Linh NGUYEN THI2,4, Roger JANKOWSKI1,2

  1. Service ORL, Institut Louis Mathieu, CHRU Nancy, Rue du Morvan, 54000 Nancy, France
  2. Université de Lorraine, Faculté de médecine, 9 Avenue de la Forêt de Haye, 54000 Nancy, France
  3. Imagerie Guilloz, Hôpital Central, CHRU Nancy, 29 Bd du Marechal de Lattre de Tassigny, 54000 Nancy, France.
  4. CIE6 Inserm: Service d’épidémiologie et évaluation cliniques, CHRU Nancy, Rue du Morvan, 54000 Nancy, France
[*]Corresponding author: Patrice GALLET, Service ORL, Institut Louis Mathieu, CHRU Nancy, Rue du Morvan, 54000 NANCY, France. Phone number : +33383155419. Fax: +33383155421. Email: patrice.gallet@yahoo.fr

Citation: GALLET P, et al. CT and MRI evaluation of nasal adenocarcinoma local extent. Cancer Research Frontiers. 2015 Apr; 1(2): 191-199. doi: 10.17980/2015.191

Copyright: @ 2015 GALLET P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Competing Interests: The authors declare that they have no competing interests.

Received December 30, 2014; Revised March 18, 2015; Accepted March 30, 2015.

 

Abstract:

BACKGROUND AND PURPOSE: The radiological evaluation of the local extent of nasal adenocarcinomas may be complex. Objectives of this study were to describe the local extent of adenocarcinomas of the olfactory cleft relatively to the natural barriers of the sino-nasal cavities and to assess the reproducibility of this evaluation.

METHODS: We retrospectively analysed a 5-year series of pre-op CT and MRI images of patients operated on nasal adenocarcinoma. The tumoral extensions were staged according to their relationships with the surrounding anatomical barriers (from d1=at distance from the barriers to d4b=invasion of the adjacent organ with resectability impossible or uncertain) by two teams (each composed of one ENT and one radiologist), who blindly analysed the radiological records twice, using a standardized grid. Reproducibility was evaluated with the kappa test.

RESULTS: 30 radiological records were analysed. Results support that the origin of woodworkers’ adenocarcinomas is in the olfactory cleft. Reproducibility was excellent for all the criteria (K=0.8) except for the relation with sphenoid sinus (K=0.5).

CONCLUSIONS: This study proposes to stage, in a precise and reproducible manner, the local extension of nasal adenocarcinomas according to their relationships with the surrounding barriers of the olfactory-ethmoidal cavities. This method of staging may help for rationalized therapeutic decision.

Keywords: nasal adenocarcinoma, woodworkers, ethmoid, reproducibility

 

 

 

 

 

 

 

 

 

 

 

 

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