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Case Report

Cancer Research Frontiers. 2016 Sept; 2(3): 432-437. doi: 10.17980/2016.432

Extremely rare case of B3/thymic carcinoma borderline tumor of the middle mediastinum in a myasthenic patient

Dania Nachira1; Maria Teresa Congedo1; Antonino Mulè2; Damiano Arciuolo2; Elisa Meacci1; Stefano Margaritora1

[1] Department of General Thoracic Surgery, Catholic University, Largo F.Vito,1, Rome, Italy

[2] Department of Pathology, Catholic University, Largo F.Vito,1, Rome, Italy

*Corresponding author: Dania Nachira, MD. Department of General Thoracic Surgery, Catholic University,  Largo F.Vito, 1, 00168, Rome, Italy. Telephone number: 00390630154106; Fax number: 00390630154673. Email: danynac@libero.it

Citation: Dania Nachira, et al. Extremely rare case of B3/thymic carcinoma borderline tumor of the middle mediastinum in a myasthenic patient. Cancer Research Frontiers. 2016 Sept; 2(3): 432-437. doi: 10.17980/2016.432

Copyright: @ 2016 Dania Nachira, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Competing Interests: The authors declare no competing financial interests.

Received Oct 23, 2016; Revised Jan 02, 2017; Accepted Jan 06, 2017. Published Jan 07, 2017

 

Abstract

Thymomas and thymic carcinomas are rare mediastinal tumors. Ectopic middle mediastinal thymomas/thymic carcinomas are even more rare. We report the first case of B3/thymic carcinoma borderline tumor of the middle mediastinum in a 61-year-old myasthenic woman. Preoperative chest tomography and magnetic resonance imaging documented a 4.0 × 3.5 × 2.7 cm mass in the retroinnominate space. A resection of the tumor of the middle mediastinum, associated with an extended thymectomy, was carried out through a median sternotomy. Pathological diagnosis was ectopic B3/thymic carcinoma borderline tumor, stage IIa in the Masaoka clinical staging system; the thymic tissue showed normal fatty involution. Postoperative course was uneventful and, at 1 year follow-up, the patient showed an improvement of Myasthenia Gravis and no sign of tumor recurrence.

Keywords: Ectopic thymoma, Myasthenia Gravis, Middle Mediastinum

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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