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Editorial

Cancer Research Frontiers. 2015 Feb; 1(1): 1-9. doi: 10.17980/2015.1

The international health care burden of cancers of the gastrointestinal tract and liver

 

William R. Brown1*, Dennis J. Ahnen2

1Department of Medicine, University of Colorado School of Medicine, Denver, Colorado, USA

2Department of Veterans Affairs Eastern Colorado Health Care System, and Department of Medicine, University of Colorado School of Medicine, Denver, Colorado, USA

*Corresponding author: William R. Brown, M.D., Emeritus Professor of Medicine, University of Colorado School of Medicine, Gastroenterology Division, MS B158, 12631 E. 17th Ave., Aurora, Colorado 80045, USA. Email: imesmeded@gmail.com

Citation: Brown WR, Ahnen DJ. The international health care burden of cancers of the gastrointestinal tract and liver. Cancer Research Frontiers. 2015 Feb; 1(1): 1-9. doi: 10.17980/2015.1

Copyright: @ 2014 Brown et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Competing Interests: The authors declare that they have no competing interests.

Received June 28, 2014; Accepted July 15, 2014; Published Feb 18, 2015

 

 

Abstract

Cancers of the gastrointestinal tract and liver are a major worldwide health problem, accounting for three of the top five causes of cancer death in world. Gastrointestinal cancer rates are changing over time, and trends vary around the world: Gastric and liver cancer rates are much higher in developing countries; gastric and colorectal cancer mortality has decreased dramatically in some developed countries; pancreatic cancer appears to be slowly but steadily increasing in developed countries. Encouraging advances have been made, or are being made, in the prevention of some cancers of the digestive organs: reduction in rates of cigarette smoking (especially in esophageal squamous cancer and pancreatic cancer); control of H. pylori infection in gastric cancer; early detection and screening in colorectal cancer; and the prevention and early, more effective treatment of hepatitis B and C infections in liver cancer. Appreciation of the magnitude of gastrointestinal and liver cancers, the geographic variations in their incidence, and the advances in some prevention and treatment measures may help in the management of these malignancies.

Keywords: Gastrointestinal cancer, liver cancer, gastric cancer, colorectal cancer, esophageal squamous cancer, pancreatic cancer

 

 

 

 

 

 

 

 

 

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